Donald Trump has said he plans to hit Canada with a 35% tariff on imported goods, as he warned of a blanket 15 or 20% hike for most other countries.
In a letter to Canadian Prime Minister Mark Carney, the US president wrote: "I must mention that the flow of Fentanyl is hardly the only challenge we have with Canada, which has many Tariff, and Non-Tariff, Policies and Trade Barriers."
Mr Trump's tariffs were allegedly an effort to get Canada to crack down on fentanyl smuggling, and the US president has expressed frustration with Canada's trade deficit with the US.
In a statement Mr Carney said: "Throughout the current trade negotiations with the United States, the Canadian government has steadfastly defended our workers and businesses. We will continue to do so as we work towards the revised deadline of August 1."
He added: "Canada has made vital progress to stop the scourge of fentanyl in North America. We are committed to continuing to work with the United States to save lives and protect communities in both our countries."
Mr Trump has sent a series of tariff letters to 23 countries so far, including one putting a 50% tariff on Brazil in part for the ongoing trial of its former president Jair Bolsonaro for trying to stay in office after he lost the election in 2022.
Mr Trump was similarly indicted for his efforts to overturn his election loss in 2020.
The higher rates would go into effect on 1 August.
Shortly after Mr Trump unveiled his "Liberation Day" tariffs on 2 April, there was a huge sell-off on the financial markets. The US president later announced a 90-day negotiating period, during which a 10% baseline tariff would be charged on most imported goods.
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But in an interview with Sky News's partner network NBC News, Mr Trump said he plans to impose higher blanket tariffs on most US trade partners.
"We're just going to say all of the remaining countries are going to pay, whether it's 20% or 15%. We'll work that out now," he said.
He added: "I think the tariffs have been very well-received. The stock market hit a new high today."
The US and UK signed a trade deal in June, with the US president calling it "a fair deal for both" and saying it will "produce a lot of jobs, a lot of income".
Sir Keir Starmer said the document "implements" the deal to cut tariffs on cars and aerospace, adding: "So this is a very good day for both of our countries - a real sign of strength."
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The US president also teased a "major statement" he will make on Russia over its war with Ukraine.
"I'm disappointed in Russia, but we'll see what happens over the next couple of weeks," he said.
"I think I'll have a major statement to make on Russia on Monday."

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It comes as Russia's deputy foreign minister, Sergei Ryabkov, said a new round of talks between Moscow and Washington on bilateral problems could take place before the end of the summer.