Dunkley's retention upon Wyatt-Hodge's return was a clear sign of England's thinking.
Alice Capsey, who made a match-winning 74 not out against New Zealand last month when standing in for Wyatt-Hodge, was pushed down to number four.
Discussion over the England top order's ability to hit boundaries was dampened by Freya Kemp's hitting in the win in Bristol on Saturday and the line-up is likely to remain for Tuesday's series decider in Taunton.
Dunkley also made a 51-ball century as opener during England's intra-squad series in South Africa in March.
A further decision will need to be made, however, once captain Nat Sciver-Brunt recovers from her calf injury, possibly in time for next week's official warm-ups against India and Australia.
Those are England's final fixtures before the World Cup begins on 12 June.
"I've opened the batting with Sophia Dunkley for a number of years now and we all know how good Sophia is at taking the game on from ball one at her best," Wyatt-Hodge said.
"It's not an easy thing to do, especially when the ball's swinging and moving off the pitch.
"Dunks has been so successful at the top and we've put some good partnerships on together, so I'm really looking forward to getting out there with her tomorrow [Tuesday] and in the World Cup as well."

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